U.S. Code of Federal Regulations
Regulations most recently checked for updates: Aug 29, 2025
§ 582.5013 - Ascorbic acid.
(a) Product. Ascorbic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5017 - Aspartic acid.
(a) Product. Aspartic acid (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5049 - Aminoacetic acid.
(a) Product. Glycine (aminoacetic acid).
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5065 - Linoleic acid.
(a) Product. Linoleic acid prepared from edible fats and oils and free from chick-edema factor.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5118 - Alanine.
(a) Product. Alanine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5145 - Arginine.
(a) Product. Arginine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5159 - Biotin.
(a) Product. Biotin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5191 - Calcium carbonate.
(a) Product. Calcium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5195 - Calcium citrate.
(a) Product. Calcium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5201 - Calcium glycerophosphate.
(a) Product. Calcium glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5210 - Calcium oxide.
(a) Product. Calcium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5212 - Calcium pantothenate.
(a) Product. Calcium pantothenate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5217 - Calcium phosphate.
(a) Product. Calcium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5223 - Calcium pyrophosphate.
(a) Product. Calcium pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5230 - Calcium sulfate.
(a) Product. Calcium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5245 - Carotene.
(a) Product. Carotene.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5250 - Choline bitartrate.
(a) Product. Choline bitartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5252 - Choline chloride.
(a) Product. Choline chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5260 - Copper gluconate.
(a) Product. Copper gluconate.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.005 percent in accordance with good manufacturing or feeding practice.
§ 582.5271 - Cysteine.
(a) Product. Cysteine (L-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5273 - Cystine.
(a) Product. Cystine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5301 - Ferric phosphate.
(a) Product. Ferric phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5304 - Ferric pyrophosphate.
(a) Product. Ferric pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5306 - Ferric sodium pyrophosphate.
(a) Product. Ferric sodium pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5308 - Ferrous gluconate.
(a) Product. Ferrous gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5311 - Ferrous lactate.
(a) Product. Ferrous lactate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5315 - Ferrous sulfate.
(a) Product. Ferrous sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5361 - Histidine.
(a) Product. Histidine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5370 - Inositol.
(a) Product. Inositol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5375 - Iron reduced.
(a) Product. Iron reduced.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5381 - Isoleucine.
(a) Product. Isoleucine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5406 - Leucine.
(a) Product. Leucine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5411 - Lysine.
(a) Product. Lysine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5431 - Magnesium oxide.
(a) Product. Magnesium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5434 - Magnesium phosphate.
(a) Product. Magnesium phosphate (di- and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5443 - Magnesium sulfate.
(a) Product. Magnesium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5446 - Manganese chloride.
(a) Product. Manganese chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5449 - Manganese citrate.
(a) Product. Manganese citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5452 - Manganese gluconate.
(a) Product. Manganese gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5455 - Manganese glycerophosphate.
(a) Product. Manganese glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5458 - Manganese hypophosphite.
(a) Product. Manganese hypophosphite.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5461 - Manganese sulfate.
(a) Product. Manganese sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5464 - Manganous oxide.
(a) Product. Manganous oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5470 - Mannitol.
(a) Product. Mannitol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5475 - Methionine.
(a) Product. Methionine.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5477 - Methionine hydroxy analog and its calcium salts.
(a) Product. Methionine hydroxy analog and its calcium salts.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5530 - Niacin.
(a) Product. Niacin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5535 - Niacinamide.
(a) Product. Niacinamide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5580 - D-Pantothenyl alcohol.
(a) Product. D-Pantothenyl alcohol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5590 - Phenylalanine.
(a) Product. Phenylalanine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5622 - Potassium chloride.
(a) Product. Potassium chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5628 - Potassium glycerophosphate.
(a) Product. Potassium glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5634 - Potassium iodide.
(a) Product. Potassium iodide.
(b) Tolerance. 0.01 percent.
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt as a source of dietary iodine in accordance with good manufacturing or feeding practice.
§ 582.5650 - Proline.
(a) Product. Proline (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5676 - Pyridoxine hydrochloride.
(a) Product. Pyridoxine hydrochloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5695 - Riboflavin.
(a) Product. Riboflavin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5697 - Riboflavin-5-phosphate.
(a) Product. Riboflavin-5-phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5701 - Serine.
(a) Product. Serine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5772 - Sodium pantothenate.
(a) Product. Sodium pantothenate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5778 - Sodium phosphate.
(a) Product. Sodium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5835 - Sorbitol.
(a) Product. Sorbitol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5875 - Thiamine hydrochloride.
(a) Product. Thiamine hydrochloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5878 - Thiamine mononitrate.
(a) Product. Thiamine mononitrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5881 - Threonine.
(a) Product. Threonine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5890 - Tocopherols.
(a) Product. Tocopherols.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5892 - a-Tocopherol acetate.
(a) Product. a-Tocopherol acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5915 - Tryptophane.
(a) Product. Tryptophane (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5920 - Tyrosine.
(a) Product. Tyrosine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5925 - Valine.
(a) Product. Valine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5930 - Vitamin A.
(a) Product. Vitamin A.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5933 - Vitamin A acetate.
(a) Product. Vitamin A acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5936 - Vitamin A palmitate.
(a) Product. Vitamin A palmitate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5945 - Vitamin B12.
(a) Product. Vitamin B
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5950 - Vitamin D2.
(a) Product. Vitamin D
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5953 - Vitamin D3.
(a) Product. Vitamin D
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5985 - Zinc chloride.
(a) Product. Zinc chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5988 - Zinc gluconate.
(a) Product. Zinc gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5991 - Zinc oxide.
(a) Product. Zinc oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.